Porcine dynorphin A(1-13)

CAS No. 72957-38-1

Porcine dynorphin A(1-13) ( Dynorphin A Porcine Fragment 1-13 )

Catalog No. M29878 CAS No. 72957-38-1

Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 133 Get Quote
10MG 211 Get Quote
25MG 437 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote

Biological Information

  • Product Name
    Porcine dynorphin A(1-13)
  • Note
    Research use only, not for human use.
  • Brief Description
    Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.
  • Description
    Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.(In Vivo):Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time.
  • Synonyms
    Dynorphin A Porcine Fragment 1-13
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Κ opioid receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    72957-38-1
  • Formula Weight
    1604
  • Molecular Formula
    C75H126N24O15
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : ≥ 60 mg/mL (37.41 mM)
  • SMILES
    ——
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75.
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