Porcine dynorphin A(1-13)

CAS No. 72957-38-1

Porcine dynorphin A(1-13) ( Dynorphin A Porcine Fragment 1-13 )

Catalog No. M29878 CAS No. 72957-38-1

Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 133 Get Quote
10MG 211 Get Quote
25MG 437 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
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Biological Information

  • Product Name
    Porcine dynorphin A(1-13)
  • Note
    Research use only, not for human use.
  • Brief Description
    Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.
  • Description
    Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.(In Vivo):Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time.
  • Synonyms
    Dynorphin A Porcine Fragment 1-13
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Κ opioid receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    72957-38-1
  • Formula Weight
    1604
  • Molecular Formula
    C75H126N24O15
  • Purity
    >98% (HPLC)
  • Solubility
    H2O : ≥ 60 mg/mL (37.41 mM)
  • SMILES
    ——
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75.
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