Porcine dynorphin A(1-13)
CAS No. 72957-38-1
Porcine dynorphin A(1-13) ( Dynorphin A Porcine Fragment 1-13 )
Catalog No. M29878 CAS No. 72957-38-1
Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 133 | Get Quote |
|
10MG | 211 | Get Quote |
|
25MG | 437 | Get Quote |
|
100MG | Get Quote | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
Biological Information
-
Product NamePorcine dynorphin A(1-13)
-
NoteResearch use only, not for human use.
-
Brief DescriptionPorcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.
-
DescriptionPorcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment.(In Vivo):Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time.
-
SynonymsDynorphin A Porcine Fragment 1-13
-
PathwayOthers
-
TargetOther Targets
-
RecptorΚ opioid receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number72957-38-1
-
Formula Weight1604
-
Molecular FormulaC75H126N24O15
-
Purity>98% (HPLC)
-
SolubilityH2O : ≥ 60 mg/mL (37.41 mM)
-
SMILES——
-
Chemical Name
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75.
molnova catalog
related products
-
NSC 4810
——
-
CID 16020046
CID16020046 is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast.
-
Regelidine
Regelidine is a natural product from Tripterygium regelii.